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Yutaka Osuga Selected Research

Endometriosis

1/2024Efficacy and safety of a novel pain management device, AT-04, for endometriosis-related pain: study protocol for a phase III randomized controlled trial.
11/2023Characterization of a fluorescence imaging probe that exploits metabolic dependency of ovarian clear cell carcinoma.
1/2023A Case of Ruptured Exophytic Uterine Artery Pseudoaneurysm without Specific Risk Factors That Manifested Seven Days after Vaginal Delivery.
12/2022Prediction of the final menstrual period in women taking Dienogest using estradiol and follicle-stimulating hormone values: a case-control study.
12/2022Evaluation of atherosclerosis-related biomarkers during perimenopause: A prospective cohort study in women with endometriosis.
11/2022Elevated phosphorylation of estrogen receptor α at serine-118 in ovarian endometrioma.
10/2022Impact of Chronic Exposure to Endometriosis on Perinatal Outcomes: Establishment of a Mouse Model.
7/2022Long-term conservative management of symptomatic bladder endometriosis: A case series of 17 patients.
1/2022Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain compared with leuprorelin in Japanese women: a phase 3, randomized, double-blind, noninferiority study.
1/2022Trophic and immunomodulatory effects of adipose tissue derived stem cells in a preclinical murine model of endometriosis.
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Yutaka Osuga Research Topics

Disease

97Endometriosis
01/2024 - 03/2003
65Neoplasms (Cancer)
03/2024 - 01/2002
29Endometrial Neoplasms (Endometrial Cancer)
03/2024 - 12/2005
26Inflammation (Inflammations)
02/2024 - 05/2003
20Pre-Eclampsia (Preeclampsia)
02/2024 - 05/2003
17Adenomyosis
12/2023 - 03/2006
17Leiomyoma (Uterine Fibroids)
12/2022 - 12/2005
15Uterine Cervical Neoplasms (Cancer of the Cervix)
08/2023 - 01/2013
14Ovarian Neoplasms (Ovarian Cancer)
12/2023 - 01/2016
13Pain (Aches)
01/2024 - 09/2011
13Dysmenorrhea (Menstrual Pain)
01/2023 - 01/2013
12Infertility (Sterility)
08/2023 - 01/2012
11Carcinoma (Carcinomatosis)
09/2023 - 05/2016
10Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
01/2024 - 05/2014
10Hemorrhage
12/2023 - 01/2008
9Carcinogenesis
04/2023 - 12/2014
7Ascites
03/2022 - 01/2016
6Hypoxia (Hypoxemia)
01/2022 - 10/2003
6Metrorrhagia (Spotting)
01/2021 - 02/2013
5Menorrhagia
01/2023 - 01/2019
5Pelvic Pain
01/2022 - 10/2014
5Uterine Hemorrhage (Uterine Bleeding)
10/2020 - 11/2010
5Premature Birth (Birth, Premature)
08/2020 - 11/2013
4Pregnancy Complications
02/2024 - 08/2014
4Neoplasm Metastasis (Metastasis)
07/2022 - 01/2014
4Cysts
03/2022 - 03/2003
4Fibrosis (Cirrhosis)
01/2022 - 10/2005
4Body Weight (Weight, Body)
10/2020 - 04/2019
3Hyperandrogenism
04/2024 - 01/2019
3Endometrial Hyperplasia
11/2023 - 02/2013
3Polyps
10/2023 - 05/2011
3Hypertension (High Blood Pressure)
05/2023 - 05/2021
3False Aneurysm (Pseudoaneurysm)
01/2023 - 11/2010
3Fever (Fevers)
01/2022 - 07/2014
3Autoimmune Diseases (Autoimmune Disease)
01/2022 - 10/2019

Drug/Important Bio-Agent (IBA)

20Proteins (Proteins, Gene)FDA Link
03/2024 - 08/2002
19dienogestFDA Link
12/2022 - 05/2008
15Gonadotropin-Releasing Hormone (GnRH)FDA Link
10/2023 - 08/2002
15Estrogens (Estrogen)FDA Link
12/2022 - 01/2002
15Progestins (Progestagens)IBA
11/2022 - 04/2007
15CytokinesIBA
01/2022 - 08/2008
13Messenger RNA (mRNA)IBA
12/2023 - 11/2005
10Oral ContraceptivesIBA
03/2022 - 05/2011
9Hormones (Hormone)IBA
12/2022 - 01/2002
8Histones (Histone)IBA
03/2024 - 01/2019
8Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2021 - 05/2003
8Interleukin-8 (Interleukin 8)IBA
10/2020 - 10/2003
8Estradiol (Delestrogen)FDA LinkGeneric
08/2020 - 12/2006
7Histone MethyltransferasesIBA
10/2022 - 06/2017
7Leuprolide (Lupron)FDA LinkGeneric
01/2022 - 01/2019
7InterleukinsIBA
01/2020 - 10/2003
6Biomarkers (Surrogate Marker)IBA
12/2022 - 03/2014
6Cisplatin (Platino)FDA LinkGeneric
03/2022 - 06/2015
6relugolixIBA
01/2022 - 01/2019
6EnzymesIBA
01/2020 - 10/2004
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2018 - 02/2009
5AndrogensIBA
01/2024 - 01/2020
5Estrogen ReceptorsIBA
11/2022 - 01/2013
5Small Interfering RNA (siRNA)IBA
10/2022 - 10/2016
5LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
01/2022 - 11/2005
5Progesterone Receptors (Progesterone Receptor)IBA
01/2022 - 01/2013
5Therapeutic UsesIBA
08/2020 - 01/2008
5Interleukin-17 (Interleukin 17)IBA
10/2019 - 03/2008
5Proteinase-Activated ReceptorsIBA
01/2012 - 06/2005
5AdiponectinIBA
03/2010 - 10/2005
4ThrombomodulinIBA
02/2024 - 01/2021
4Poly(ADP-ribose) Polymerase InhibitorsIBA
12/2023 - 03/2014
4Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric
11/2023 - 04/2007
4Hemoglobins (Hemoglobin)IBA
01/2023 - 08/2018
4Indicators and Reagents (Reagents)IBA
12/2022 - 05/2010
4DNA (Deoxyribonucleic Acid)IBA
10/2022 - 03/2014
4LigandsIBA
01/2021 - 02/2009
4ProgesteroneFDA LinkGeneric
01/2021 - 12/2008
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2021 - 01/2008
4Interleukin-6 (Interleukin 6)IBA
10/2018 - 07/2011
4ResveratrolIBA
10/2016 - 03/2014
4Interleukin-4 (Interleukin 4)IBA
04/2013 - 08/2008
4ThrombinFDA Link
10/2012 - 08/2003
3InterferonsIBA
03/2024 - 02/2019
3HMGB1 Protein (HMG1)IBA
02/2024 - 08/2011
3Analgesics (Analgesic Drugs)IBA
12/2023 - 09/2017
3Carboplatin (JM8)FDA LinkGeneric
12/2023 - 11/2020
3SuspensionsIBA
11/2023 - 04/2017
3Bevacizumab (Avastin)FDA Link
09/2023 - 10/2017
3Levonorgestrel (Plan B)FDA LinkGeneric
01/2023 - 10/2015
3Anti-Bacterial Agents (Antibiotics)IBA
03/2022 - 07/2014
3Doxorubicin (Adriamycin)FDA LinkGeneric
03/2022 - 06/2017
3ulipristal acetateFDA Link
01/2022 - 01/2021

Therapy/Procedure

43Therapeutics
12/2023 - 04/2007
21Hysterectomy
12/2023 - 03/2006
14Drug Therapy (Chemotherapy)
12/2023 - 01/2011
10Uterine Myomectomy
10/2023 - 11/2009
8Cesarean Section (Caesarean Section)
03/2023 - 11/2010
5Conservative Treatment
07/2022 - 04/2007
4Oral Administration
11/2023 - 09/2020
4Aftercare (After-Treatment)
02/2022 - 10/2017
3Laparotomy
11/2023 - 04/2002
3Cystectomy
07/2023 - 07/2015
3Drug Tapering
05/2023 - 10/2020
3Radiotherapy
03/2023 - 07/2015